• These reactions are used to account

  2021-03-23

  

  These reactions are used to account for variations in protein solubility or vesicle recovery. For example, with DGKθ we have found it necessary to maintain the purified enzyme in a solution of 0.01% DDM (DGK-D dilution buffer) in the control reaction to prevent enzyme loss due to aggregation or adhe

• The role of ARA cyp metabolites

  2021-03-23

  

  The role of ARA-cyp450 metabolites in the liver is still unclear [44]. However, ARA-cyp450 genes metabolize other fatty acids such lauric and palmitic HBC [45]. It was found that decreased cyp4a expression caused fatty livers through reduction of fatty acid metabolism [46]. In this study, we found

• As the communications interface was developed

  2021-03-22

  

  As the communications interface was developed by two separate organisations with differing software processes and tools, a modular approach to the safety case was deemed appropriate. The modular approach related the communications interface safety argument to the safety arguments for both the ACS an

• In some of our studies we examined the occurrence

  2021-03-22

  

  In some of our studies we examined the occurrence of ERβ and SHBG and a possible colocalization between them. Fig. 5 shows that there is no big difference in the occurence of ERβ after short time (A) as well as long time (B) treatment with E2. We can find the receptor at the cell membrane as well as

• As shown in Fig there are two mechanisms for

  2021-03-22

  

  As shown in Fig. 9, there are two mechanisms for the removal of the Va-acyl group from PC to make it available for incorporation into TAG with DGATs' acting at the final acylation step. ①: Transfer of Va from PC to the acyl-CoA pool. This process can be driven by the reverse action of acyl- CoA:lyso

• br Acknowledgments br Introduction Cysteinyl leukotrienes Cy

  2021-03-22

  

  Acknowledgments Introduction Cysteinyl leukotrienes (CysLTs), LTC4, LTD4 and LTE4, are 5-lipoxygenase pathway metabolites of arachidonic 9-cis-Retinoic Acid australia and deeply involved in bronchial asthma via activation of CysLT1 receptors [1], [2]. Specific CysLT1 receptor antagonists, inc

• Several in vivo human studies have produced conflicting resu

  2021-03-22

  

  Several in vivo human studies have produced conflicting results for evaluating the inhibition of OCs on the metabolism of CYP3A substrates. Balogh et al. [12] demonstrated an approximately 25% inhibition of CYP3A activities in vivo after the administration of an OC containing 30μg of ethinylestradio

• To elucidate the potential mechanism

  2021-03-22

  

  To elucidate the potential mechanism underlying osteosarcoma cell growth decrease by CDK4 inhibition, flow cytometry analysis was used to determine UNC 0646 and apoptosis in human osteosarcoma cells after palbociclib treatment. The results showed that osteosarcoma cells were arrested in G1 phase of

• TR provides requirements for qualification of commercial

  2021-03-22

  

  TR-107330 (1996) provides requirements for qualification of commercial PLC. It uses the criteria of NUREG/CR-6421. EPRI TR-104159 (1995) includes experience about dedicating COTS SW for PLC-based digital systems such as DAFAS (Diverse Auxiliary Feedwater Actuation System) and Emergency Diesel Bus Lo

• The strong adsorption of amines to the

  2021-03-22

  

  The strong adsorption of amines to the stationary phase of gas chromatography (GC) columns causes issues such as tailing, ghosting and low reproducibility [12], [13]. A common practice to overcome this problem is the chemical derivatisation of amines prior to GC analysis [14]. Comprehensive reviews

• In this study we reported that over expressed endogenous

  2021-03-22

  

  In this study, we reported that over-expressed endogenous central ET-1 exerted anti-allodynic and anti-hyperalgesic effects on SNL-induced NP for the first time. Furthermore, we showed that ETA-R mRNA Capecitabine synthesis together with the level of ET-1 was increased in the CNS up to 21days after

• br Conflicts of interest br

  2021-03-22

  

  Conflicts of interest Author contributions Acknowledgements This work was supported by the University of Brescia (ex 60%) and Siderurgica Leonessa research funds to AF. RR was supported by Associazione Italiana per la Ricerca sul Cancro - AIRC (MFAG 18459 grant). We are grateful to Umberto

• br Conflict of interest statement br Introduction

  2021-03-19

  

  Conflict of interest statement Introduction Endothelins (ETs) are a family of multifunctional, naturally occurring peptides with long-lasting vasoconstrictor and pressor effects (Zhou et al., 2004). They are synthesized as a large protein, the pre-proET-1 or Big ET-1, which is subsequently cle

• The development of novel approaches to

  2021-03-19

  

  The development of novel approaches to study GPCR-mediated transactivation in live Temozolomide is important, and this study describes a unique BRET-based quantification of Grb2 recruitment to the EGFR as a direct readout of GPCR-mediated transactivation. We have previously used the recruitment of

• br EBV Infection Epstein Barr virus EBV human

  2021-03-19

  

  EBV Infection Epstein–Barr virus (EBV, human herpesvirus 4) was discovered 50 years ago, when Epstein, Achong, and Barr used electron microscopy to identify viral particles in Burkitt's lymphoma cells. It belongs to the lymphocryptovirus (LCV) genus of the gammaherpesvirus subfamily (Fig. 1A). Th

16380 records 702/1092 page Previous Next First page 上5页 701702703704705 下5页 Last page