• Conflicts of interest br Acknowledgments This article

  2019-06-18

  

  Conflicts of interest Acknowledgments This article was supported by grants from the Ministry of Science and Technology, Executive Yuan (MOST 103-2314-B-010-043-MY3), and Taipei Veterans General Hospital (V103C-112; V104C-095; and V105C-096). We also appreciate the Clinical Research Core Laborato

• Surgery especially modified radical mastectomy is the gold s

  2019-06-17

  

  Surgery, especially modified radical mastectomy, is the “gold standard” for the treatment of male breast cancer. Postoperative adjuvant radiotherapy is recommended for male patients with large breast cancer and axillary lymph node and chest muscle involvement; it can reduce the risk of local cancer

• BIIE 0246 Introduction Several types of cancers including th

  2019-06-17

  

  Introduction Several types of cancers, including those originating in the breast, prostate, and lung, have a propensity to metastasize to the bones [1,2]. Bone metastases severely impair skeletal metabolism, and result in important clinical sequelae, such as excruciating chronic bone pain and the s

• Dexamethasone with its anti inflammatory properties has been

  2019-06-17

  

  Dexamethasone, with its anti-inflammatory properties, has been shown to be an effective medication in the treatment of pain flare and is hypothesized to prevent the phenomenon as well [12]. Despite a lack of literature investigating this hypothesis, currently published phase I and II trials have pro

• br Case report His physical examination and basic laboratory

  2019-06-17

  

  Case report His physical examination and basic laboratory data were normal. No organic heart disease other than dextrocardia was detected on electrocardiography, chest radiography, and echocardiography (Fig. 1). A head-up tilt test (HUT) was performed according to the ESC/ACC guidelines [7,8]. T

• We would like to also clarify that we do not

  2019-06-17

  

  We would like to also clarify that we do not underestimate the CIs in our study through the assumption that GDP was observed independently for every child in the survey. The multilevel design and clustering of standard errors at the survey level accounts for the fact that GDP is not observed indepen

• Entre estas perspectivas subyace un complejo concepto de

  2019-06-17

  

  Entre estas perspectivas subyace un complejo concepto de paz que implica una relación dialéctica con la justicia, pues ésta “no consiste únicamente en el pacifismo TAI-1 cost ultranza o en la ausencia de guerra”. En ello radica el interés profundo de la tl por la esperanza cristiana de una paz efect

• In contrast to adults PBL

  2019-06-17

  

  In MHY1485 to adults, PBL in children is regarded as a clinical entity that is distinct from its adult counterpart. Like many other pediatric malignancies, PBL is considered a systemic disease in children. In small retrospective studies, PBL in children is characterized by rapid progression, a high

• As en una parodia llevada al extremo del

  2019-06-15

  

  Así, en una parodia llevada al extremo del absurdo de esta escritura blanca o vacía, Amélie descubre finalmente que los tesoros vivientes no escriben, sus libros son “maquetas empastadas con las hojas en blanco” (55). Tekendogo es un país donde la dictadura se legitima VE-822 manufacturer través de

• br In the past year migration to

  2019-06-15

  

  In the past year, migration to Europe from Africa and the Middle East has reached unprecedented levels. In 2016, 181 405 migrants reached the shores of Italy and more than 5000 died trying to reach the southern coasts of Europe. Many migrants seek to escape war, poverty, persecution, or ill treatm

• br Conclusions Based on our findings using a chronic

  2019-06-15

  

  Conclusions Based on our findings using a chronic animal model in vivo that repeated VF and defibrillation, not shocks, are associated with striking CaMKII activation, together with accumulating evidence that CaMKII is crucially involved in cellular processes for HF, it is conceivable that CaMKII

• sirtuin Introduction Ewing s sarcoma ES is

  2019-06-15

  

  Introduction Ewing\'s sarcoma (ES) is a high-grade neoplasm representing the second most common primary bone malignancy in both children and adults. With a peak incidence at 15 years, this disease accounts for 2% of childhood cancers [1–3]. ES is defined as a bone tumor which may occur at any site

• br Interpretation of identified genetic variants and genetic

  2019-06-15

  

  Interpretation of identified genetic variants and genetic counseling Although the current expert consensus statement recommends that comprehensive or BrS1 (SCN5A) targeted BrS genetic testing can be useful for genetic testing [63], not all the published SCN5A mutations in BrS have been subjected

• Causative genes for ARVC and their

  2019-06-15

  

  Causative genes for ARVC and their respective characteristics are summarized in Table 1. Desmosome genes for ARVC Other causative genes for ARVC Although more than half of ARVC patients carry mutations in desmosome genes, other genes have also been reported as causative genes for ARVC (Table

• will be remembered as an exceptional

  2019-06-15

  

  2013 will be remembered as an exceptional year in shaping our strategy to control HIV/AIDS. Indeed, a few weeks after the 30th anniversary of the discovery of the virus, a decisive step was made in deciding how to use antiretroviral therapy (ART) for treatment and prevention worldwide. New WHO publi

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